CV
EDUCATION
July 2017 - Current
University of Cincinnati, Cincinnati, OH
Ph.D. Candidate, Immunology Graduate Program
August 2013 - May 2015
Ball State University, Muncie, IN
M.S., Biology
August 2009 - May 2013
Ball State University, Muncie, IN
B.S., Biology
RESEARCH
July 2018 – Current
University of Cincinnati, Cincinnati, OH
Ph.D. Candidate, Division of Immunology
Advisor: Emily R. Miraldi, Ph.D.
Modeling genetic contributions to immune-cell behavior with gene regulatory networks.
Jan. 2016 – July 2017
Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
Research Assistant, Division of Allergy and Immunology
Advisor: Andrew Lindsley, MD, Ph.D.
Characterizing a mouse model of type 1 Kabuki syndrome
Aug. 2014 – Dec. 2015
Eli Lilly and Company, Indianapolis, IN
Academic Contractor, Cardiovascular Disease and Diabetic Complications
Advisors: Marian Mosior, Ph.D. and Wei Ni, Ph.D.
Characterization of the effects of NRG-1 on HepG2 cell metabolism
Description: I was part of a cooperative program between Eli Lilly and Company and Ball State University. I worked for 1.5 years in the Lilly labs performing my master’s thesis research in drug discovery and characterization with a focus on modulating triglyceride metabolism.
http://cardinalscholar.bsu.edu/handle/123456789/200064
Aug. 2013 - July 2014
Ball State University, Muncie, IN
Research Assistant, Department of Biology
Advisors: James Olesen, Ph.D.
Characterizing the role of TAL1 in T-cell acute lymphoblastic leukemia
PUBLICATIONS
2021
- X Lu, X Chen, C Forney, O Donmez, D Miller, S Parameswaran, T Hong, Y Huang, M Pujato, T Cazares, ER Miraldi, JP Ray, CG de Boer, JB Harley, MT Weirauch, and LC Kottyan. Global discovery of lupus genetic risk variant allelic enhancer activity. Nature Communications
2020
- GO Pilarowski, TA Cazares, …, A Barski, HT Bjornsson, AW Lindsley. Abnormal Peyer patch development and B-cell gut homing drive IgA deficiency in Kabuki syndrome, Journal of Allergy and Clinical Immunology 145 (3), 982-992
2016
- E Schauberger, M Peinhaupt, TA Cazares, AW Lindsley, Lipid mediators of allergic disease: pathways, treatments, and emerging therapeutic targets, Current Allergy and Asthma Reports 2016
PRESENTATIONS
-
TA Cazares, maxATAC: a suite of user-friendly neural network models for transcription factor binding prediction from ATAC-seq, Cold Spring Harbor Probabilistic Modeling in Genomics 2021 (Poster)
-
TA Cazares, maxATAC: A suite of user-friendly neural network models for transcription factor binding prediction from ATAC-seq, Cincinnati Children’s Hospital Immunobiology Retreat 2020 (Poster)
-
TA Cazares, Optimizing ATAC-seq based Transcription Factor Binding Predictions for Gene Regulatory Network Inference, Cincinnati Children’s Hospital Immunobiology Retreat 2019 (Poster)
-
TA Cazares, Modeling Epstein-Barr virus transcriptional regulatory networks in lymphoblastoid cell lines, Cold Spring Harbor Systems Immunology Meeting 2019 (Poster)
-
TA Cazares, Leveraging 3D Chromatin Structure and Allele-Specific Transcription Factor Binding to Infer Transcriptional Regulatory Networks, Cincinnati Children’s Hospital Immunobiology Retreat 2018 (Poster)
-
TA Cazares, Transcriptional Regulatory Network Inference for Intestinal Myeloid Cells, Autumn Immunology Conference 2017 (Talk)
-
TA Cazares, GO Pilarowski, A Barski, HT Bjornsson, AW Lindsley, A mouse model of type 1 Kabuki syndrome with defective humoral responses to mucosal vaccination, Clinical Immunology Society Meeting 2017 (Talk)
TEACHING AND SCHOLASTIC EXPERIENCE
July 2013 – July 2014
Graduate Assistant, Department of Biology, Ball State University, IN
Oct. 2013 – May 2014
AP Biology Tutor, Muncie, IN
February 22, 2015
Indiana East Central Regional Scienc Fair Judge, Muncie, IN
AWARDS
Tuition, travel, and lodging scholarship, DeCART Bioinformatics Summer School Scholarship, University of Utah, Salt Lake City, UT (2018)
Travel Grant to Clinical Immunology Society Meeting, Seattle, WA (2017)
On-time Graduation Award (Complete degree if 4 years), Ball State University, Muncie, IN (2013)