get_compensatory_sequences
get_compensatory_sequences.Rd
Function to get 3' compensatory sequences for a given siRNA sequence.
Usage
get_compensatory_sequences(
guide.seq,
seed,
sequences,
compensatory_region_length_min = 6,
compensatory_region_length_max = NA,
limit = 100,
mismatch_ = 1,
mismatch_compensatory_region_ = 0
)
Arguments
- guide.seq
A character string representing the guide sequence.
- seed
A character string representing the seed sequence.
- sequences
A DNAStringSet object containing the sequences of the transcripts.
- compensatory_region_length_min
An integer representing the minimum length of the compensatory region.
- compensatory_region_length_max
An integer representing the maximum length of the compensatory region.
- limit
An integer representing the limit for sequence update.
- mismatch_
An integer representing the maximum number of mismatches allowed in the seed match.
- mismatch_compensatory_region_
An integer representing the maximum number of mismatches allowed in the compensatory region.